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Effects of refined black sesame oil on amiodarone-induced phlebitis


May 28, 2024


Effects of refined black sesame oil on amiodarone-induced phlebitis 

LI YanUng1, LIU Lan1, ZHAO Zihui1, FENG Cuina1, CHEN Xi

(1. the First Ward of Cardiovascular Medicine, 2. Nursing Department, Affiliated Hospital of Hebei University, Baoding, Hebei, 071000) 

Abstract: Objective To investigate effects of refined black sesame oil(sesame oil) on amiod-arone-induced phlebitis

Methods A total of 50 hospitalized patients who received intravenous infusion of amiodarone hydrochloride in department of cardiovascular medicine were randomly divided into experimental group and control group, with 25 cases in each group. One case was lost during follow-up in the control groupPatients in the experimental group were fixed with 3M transparent dressing without tension and five drops of sesame oil were applied to the skin within a 10 cm radius of the infusion site prior to the administration of amiodarone until they were completely absorbedSesame oil was used every 6 h and for 4 times in total. The indwelling needle was fixed with hydrocolloid dressing after puncture in the control group. The incidence of phlebitis of two groups was compared, and severity of phlebitis and occurrence time of phlebitis was recorded. 

Results No significant differences were found in the incidence rates of phlebitis between the two groups at different time points (P >0.05). The total incidence of phlebitis in the experimental group was lower than that in the control group (48.00% versus 83. 33%, P <0.05) , and the severity of phlebitis was lower than that in the control group, and the occurrence time of phlebitis was latter than that in the control group (P <0. 05). 

Conclusion The  application of sesame oilon the puncture sites can reduce the incidence of phlebitis caused by amiodarone hydrochloride injection, relieve the severity phlebitis, and delay the occurrence of phlebitis. 

Key words: amiodarone hydrochloridephlebitisrefined black sesame oilhydrocolloid dressingindwelling needle; 3M transparent dressing.


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